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UPDATE 1-FDA declines to approve Adamis Pharma's Zimhi to treat opioid overdose

Adamis Pharmaceuticals Corp said on Monday the U.S. Food and Drug Administration declined to approve its opioid overdose treatment, raising questions around its chemistry, manufacturing and controls (CMC). In a letter to the company, the FDA questioned the treatment’s manufacturing process, but not its safety or effectiveness, Adamis said. The drug Zimhi is a naloxone pre-filled single dose syringe used for emergency treatment of known or suspected opioid overdose. …read more […]

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Blackstone to invest $400 million in gene therapy venture with Ferring

Blackstone made its foray in the sector last year, acquiring Clarus, an investment firm specializing in life sciences. For its part, Ferring will invest $170 million in the joint venture with Blackstone, dubbed FerGene, bringing its total funding to $570 million, the companies said in a statement. …read more […]

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UPDATE 1-Sorrento Therapeutics rejects all-cash takeout proposal; shares jump

Sorrento Therapeutics Inc said on Monday it had rejected an unsolicited buyout proposal from two pharmaceutical companies, saying it significantly undervalued the drugmaker and was not in the best interests of its shareholders. The all-cash deal on Saturday offered between $3 and $5 for each of Sorrento’s outstanding shares, the company said. At the higher-end of the offer, Sorrento would have been valued at $709.4 million, while its current market capitalization stands at nearly $227 million. …read more […]