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Novartis' Zolgensma study halted by FDA amid safety questions

U.S. regulators have halted a trial of Novartis’s Zolgensma treatment after an animal study raised safety concerns, the company said on Wednesday, in a setback for the drugmaker’s plan to expand its use to older patients. The U.S. Food and Drug Administration’s partial hold on the so-called STRONG trial impacts patients aged up to five with spinal muscular atrophy (SMA) who were to receive a higher dose of the gene therapy via a spinal infusion. The hold was issued after Novartis told health authorities about the animal study’s findings that showed dorsal root ganglia (DRG) mononuclear cell inflammation, …read more […]

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UPDATE 1-Buoyant networks keep Iberdrola on track for 2019 net profit goals

Spanish renewable energy giant Iberdrola on Wednesday reiterated its double-digit net profit growth guidance for the whole year, supported by a resilient power network business in Brazil and the United States as well as higher offshore wind output. Supplying energy to more than 30 million people in Spain, the United States, Brazil and Britain, Iberdrola raked in core earnings before interest, tax, depreciation and amortisation (EBITDA) of 7.5 billion euros ($8.33 billion). …read more […]

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U.K. Election Prospect Has Market Players Scratching Their Heads

(Bloomberg) — Prime Minister Boris Johnson may be trying to break the logjam over the departure from the European Union with a general election, but for the market players the vote is another cause of uncertainty.On Tuesday after the market closed, Johnson won crucial votes in the House of Commons for the general election on Dec. 12, which now needs to be approved by the House of Lords. The benchmark FTSE 100 Index and the mid-cap FTSE 250 Index were little changed in early London trading. They fell yesterday after it became clear the opposition Labour Party backed an election.Here’s …read more […]

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Airbus cuts delivery goal on Hamburg plant snags

PARIS/HONG KONG (Reuters) – Airbus cut its full-year delivery goal for commercial jets on Wednesday, as the planemaker struggles with production delays at a newly expanded German plant. Europe’s largest aerospace group expects to deliver “around 860” airliners in 2019 instead of the 880-890 previously targeted, the company said as it posted 1.6 billion euros ($1.78 billion) in adjusted operating income for the third quarter. The revised delivery numbers and outlook “reflect the underlying actions to secure a more efficient delivery flow in the next years”, Chief Executive Guillaume Faury said in the company statement. …read more […]

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Sony logs record second-quarter profit on robust sales of image sensors for smartphones

Sony Corp on Wednesday said quarterly operating profit jumped 16% on robust image sensor sales, its strongest-ever result for the second quarter, and it raised its full-year earnings outlook. Sony raised its annual profit forecast to 840 billion yen from an earlier estimate of 810 billion yen. Apple, for instance, added a third lens to the iPhone 11 Pro model, matching the three-camera setup on flagship models for rivals like Samsung Electronics Co Ltd and Huawei Technologies Co Ltd [HWT.UL]. …read more […]

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PG&E’s CEO Comes Up Against the One Thing He Can’t Fix

(Bloomberg) — Five months ago, PG&E Corp. Chief Executive Bill Johnson walked into a room full of California lawmakers and told them he was the man who would fix the state’s largest utility.Johnson was 15 days on the job, and PG&E had just been found to have caused California’s Camp Fire, which killed 86 people, leveled an entire town and landed the company in the biggest utility bankruptcy in U.S. history. “Let’s not do it again,” he said.This week, PG&E proved its problems are far from fixed. The company’s equipment is being probed as the potential cause of at least …read more […]

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Soho China Considers $8 Billion Office Tower Sales

(Bloomberg) — Soho China Ltd. is considering selling a majority of its commercial property holdings in deals that may fetch as much as $8 billion, according to people familiar with the situation.At least eight office towers in Beijing and Shanghai are being discussed as part of the planned sales, said the people, who asked not to be named because the discussions are private.An initial batch of projects worth as much as $3 billion is being shopped to potential buyers, the people said. Sovereign wealth funds and private equity groups are among those being approached, one of the people said. Talks …read more […]

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Boeing Hearing: Pilots Association's Reaction

Oct.29 — Dennis Tajer, spokesman of the Allied Pilots Association and an American Airlines captain, talks about Boeing Co. Chief Executive Officer Dennis Muilenburg’s appearance before Congress. The CEO declined to endorse specific reforms to bolster safety oversight of the aerospace giant. Tajer speaks with Sophie Kamaruddin and Rishaad Salamat on “Bloomberg Markets: Asia.” …read more […]

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PG&E Will Issue Shutoff Rebates to Customers: California Update

(Bloomberg) — Californians in the midst of another round of blackouts as some of the season’s strongest winds fan wildfires across the state. All told, PG&E Corp., Edison International and Sempra Energy may cut power to as many as 2.5 million people to prevent live power lines from toppling into dry brush.At least 10 large wildfires are already burning across the state. High winds this week have left more than 17 million people — almost half of California’s population — facing critical fire weather conditions, according to the U.S. Storm Prediction Center. Time stamps are New York time.PG&E Will Issue …read more […]

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Oil prices drop, U.S. falls for third day as Cushing stocks rise

Oil prices slipped on Wednesday, with U.S. crude falling for a third day after an industry report that stocks at the Cushing delivery hub for the benchmark rose last week, shrugging off a drop in overall inventories. Brent crude was down 15 cents, or 0.2%, at $61.44 a barrel by 0118 GMT after gaining 2 cents on Tuesday. U.S. West Texas Intermediate (WTI) crude was down 18 cents, or 0.3%, at $55.36 a barrel, having dropped 0.5% in the previous session. …read more […]